Non-small cell lung cancer
Core of basic research: Decipher the association between driver mutation profiles (EGFR, ALK, ROS1, BRAF) and tumor subtypes, explore the mechanisms and resistance mutations (e.g., EGFR T790M) of targeted inhibitors, as well as the interaction between PD-L1 expression and immune cells in the tumor microenvironment.
Core key proteins: EGFR (receptor tyrosine kinase driving proliferation upon mutation), ALK/ROS1 (fusion proteins activating downstream signals), BRAF (MAPK pathway driver), MET (amplification or mutation leading to resistance), PD-L1/PD-1 (immune checkpoints regulating T cell activity), TP53 (tumor suppressor gene with frequent mutations), KRAS (small GTPase driving subtype upon mutation), VEGF (angiogenic factor).
Core key proteins: EGFR (receptor tyrosine kinase driving proliferation upon mutation), ALK/ROS1 (fusion proteins activating downstream signals), BRAF (MAPK pathway driver), MET (amplification or mutation leading to resistance), PD-L1/PD-1 (immune checkpoints regulating T cell activity), TP53 (tumor suppressor gene with frequent mutations), KRAS (small GTPase driving subtype upon mutation), VEGF (angiogenic factor).
Product list
-
{{item.title}}{{item.react}}{{item.applicat}}
Product list
Product name
Reactivity
Application
Related Resource Links
Related Promotional Journal Downloads
Explore Our Recommended Popular Products
More products
30,000+ high- quality products available online
Primary Antibodies, Secondary Antibodies, mIHC Kits, ELISA Kits, Proteins, Molecular Biology Products，Cell Lines，Reagents ...
Contact Us
-
400-801-6722
-
support@lamarck.cn
-
Order
-
Message